At some seasons, the route to this cache may be messier than others. The cache is close to a popular trail so please be very stealthy. In the winter, please don't leave a straightforward track to the cache. Due to the nature of some of the items in the initial contents, we don't expect equal trades but staying with the theme (once you figure it out) would be appreciated.
Updated 7/7/14 to reflect Epoch 2000 coordinates and clarify some confusing text
The container is a camoflaged 10 x 10 x 5 inch lock-n-lock which is pretty full at the start.The terrain rating is due to distance to walk coupled with potentially wet and muddy trails at certain times. The cache is NOT at the posted coordinates.
To solve for the coordinates of this cache, you will need to determine the following before leaving home. Pay particular attention to the units. We are always happy to provide advice if needed.
Cache page images are from Hubblesite.org

AB = Orion's number
CD = Distance in mly to item 108 minus 3 mly
E = Last digit in the RA of item 48
FG = Find the item with a fairly obvious correlation to the state of Kansas and subtract 1 from its number
The latitude is N AB CD.EFG
HI = Largest value in App. size of the Lagoon minus 6'
JK = Dumbell's # + 1
L = 3rd digt in declination of the Crab Nebula
MN = Trifid's number +2
The longitude is W HI JK.LMN

If the hint below isn't enough, use this link: Total Spoiler
You can check your answers for this puzzle on Geochecker.com.

Voted one of the Lansing Area's Top Caches for 2011.