Genetic Code #7 - Genetics Crossword Mystery Cache
Hidden : 10/4/2013
Difficulty:
3 out of 5
Terrain:
1.5 out of 5

Size: Size: regular (regular)

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Geocache Description:

Cache is not at the posted coordinates! As a geo-geneticist, you must solve the puzzle below:

Puzzle:

Across: N 32° __.___
 1. Reading _____ - a way of dividing the nucleotide sequence into a set of consecutive, non-overlapping triplets
2. The entirety of an organism's hereditary information
3. Binds to adenine in RNA
4. Binds to adenine in DNA
5. Amino acid precursor for tyrosine (abbr.)
6. Nucleotide triplet
7. The inherited instructions an organism carries within its genetic code
8. The sugar forming part of the RNA backbone
9. Forms hydrogen bonds with a complementary purine
10. Type of mutation that causes the replacement of a single base nucleotide with another nucleotide
11. The copying of DNA into messenger RNA in gene expression
12. Although most of a cell's DNA is contained in the cell nucleus, this cellular organelle contains its own independent genome
13. tRNA anticodon _____ is a 5-bp stem containing the anticodon
14. Won the 1958 Nobel Prize in Physiology or Medicine for discovering that bacteria can mate and exchange genes
15. A non-essential amino acid whose codons are CCU, CCC, CCA, and CCG
16. _____ Crick - co-discoverer of the DNA's structure in 1953 with James D. Watson
17. 1989 Nobel Prize in Physiology or Medicine co-winner with J. Michael Bishop for discovery of the cellular origin of retroviral oncogenes
18. Frame_____ mutation - caused by insertions or deletions of a number of nucleotides in a DNA sequence that is not divisible by three
19. Hydrophobic amino acid encoded by UUA, UUG, CUU, CUC, CUA, and CUG (abbr.)
20. The sugar forming part of the DNA backbone
21. The process of producing two identical copies from one original DNA molecule (same as 5-Down)
22. Methionine abbreviation
23. The process in which cellular ribosomes create proteins

Down: W 097° __.___
 1. _____ _____ - carries amino acids to the ribosome by specific codons in messenger RNA
2. 1968 Nobel Prize co-winner in Physiology or Medicine in 1968 for describing the structure of alanine transfer RNA, thereby linking DNA and protein synthesis
3. Awarded the Nobel Prize for Physiology or Medicine in 1959 for his work on the synthesis of RNA
4. _____ Gilbert - awarded the 1980 Nobel Prize in Chemistry for pioneering work in devising methods for determining the sequence of nucleotides in a nucleic acid
5. The process of producing two identical copies from one original DNA molecule (same as 20-Across)
6. Composed of a nucleobase, a pentose (ribose or deoxyribose) and at least one phosphate group
7. _____ mutation - a point mutation in a sequence of DNA that results in a premature stop codon
8. Selenocysteine abbreviation
9. An essential amino acid whose codons are GUU, GUC, GUA, and GUG
10. Amino acid monomers containing approximately 50 amino acids or less
11. _____ _____(s) - made of amine and carboxylic acid functional groups and are the building blocks of proteins
12. Any nucleotide sequence within a gene that is removed by RNA splicing while the final mature RNA product of a gene is being generated
13. Large biological molecule consisting of one or more chains of amino acids
14. Cellular organelle that is the primary site of protein synthesis
15. Chemical entity consisting of two structurally similar monomers joined by bonds (ie insulin)
16. _____ mutation - mutations that either do not result in a change to the amino acid sequence of a protein or result in the insertion of an alternative amino acid with similar properties to that of the original amino acid
17. The study of genes, heredity, and variation in living organisms
18. Shared the 1962 Nobel Prize in Physiology or Medicine with Watson and Crick for the discovery of the structure of DNA
19. Binds to thymine in DNA
20. Carboxylic acid abbreviation
21. A neutral molecule with a positive and a negative electrical charge (ie amino acid)
22. A heterocyclic aromatic organic compound consisting of a pyrimidine ring fused to an imidazole ring (ie adenine and guanine)

***Do not forget the Bonus Clue.***

You can validate your puzzle solution with certitude.

Additional Hints (Decrypt)

Pnpur: oruvaq pbyhza

Decryption Key

A|B|C|D|E|F|G|H|I|J|K|L|M
-------------------------
N|O|P|Q|R|S|T|U|V|W|X|Y|Z

(letter above equals below, and vice versa)


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