This road to Adamsville used to lead to a ferry at the Chickasawhay river. The ferry would take you across the river to Polley Wiggle road, which is where Adamsville was located. Adamsville was settled by Dr. Bodo Otto Adams before the civil war.
From http://www.usgennet.org/usa/ms/county/greene/byron.htm:
"Dr. Bodo Otto Adams was born in Philadelphia, Pennsylvania in March 1782. He was from a very affluent family. After medical and chemical education he practiced medicine in Mobile, Alabama. Before the Civil War he bought a great tract of land in Mississippi along the Chickasawhay River. There he built his home, and developed a medical practice and a plantation. Dr. Adams accumulated quite a fortune in real estate and virgin pine timber. Families settled in the area that was called Adamsville. It was about twelve miles north of Leakesville. Dr. Adams was also the community's postmaster. After the Civil War ended, the doctor's health began to fail as he grew old. He wrote Captain McClean, his nearest kinsman in New Orleans and asked him to move his family to Adamsville and become heir to his wealth. At first, Mary Elizabeth Knight McClean, Isadora's mother, was reluctant to move her family from the city to backwoods of Mississippi. Nevertheless, the McCleans moved to Adamsville in 1867 when Isadora was 16 years old. There were five McClean girls and one boy, the youngest of the siblings. The family didn't arrive in Mississippi too soon, for Dr. Adams died on December 30, 1867."
Also, according to the genealogy trails website, he served in the war of 1812.
The town and the ferry are no longer there, but you will find a cache before you come to the end of the road. You'll be looking for a camouflage container. Inside you'll find a logbook, stamp, and inkpad. Please wipe off excess ink from the stamp and return them to the container!