騎西（きさい）城の築城時期や築城時の城主は不明ですが、康正元年（1455）深谷上杉氏の城であった騎西城を守っていた長尾・庁鼻和（こばなわ）氏を古河公方足利成氏が攻略したのが初見です。
また、永禄六年（1563）には、小田助三郎が守る騎西城を上杉輝虎（謙信）が攻め落としています。
徳川家康が関東に入った天正十八年(1590)には、松平康重が二万石で騎西城の城主になっています。
騎西の大英寺の開基や日出安の保寧寺への寺領の付与は松平康重によるものです。
その後、大久保忠常・忠職（ただもと）父子が城主となり、玉敷神社を現在の地に遷座するなど、城下町騎西の再編を行いました。
そして寛永九年(1632）、忠職の美濃国加納城移封に伴い、騎西城は廃城となりました。
昭和五年からの騎西城発掘調査により、城の周囲には二重の障子掘が巡らされ、堀幅の最大は45mあったことが判り、激戦に備えた厳重な構えであったことが判明しました。
騎西城の城郭・武家屋敷跡からは、戦国時代から江戸時代初期にかけての武器・武具・生活用具が発掘されています。
出土品は多様で、国内外の陶磁器、矢じり、鎧金具、火打金などの金属製品や、これらの他にも大量の漆、木製品も出土しています。
また、その他、漆黒の兜、金色に輝く馬の鐙、鶴文の漆椀に加え、下駄、荷札、呪符、護符など、いずれも城下の暮らしぶりを鮮やかに蘇らせる品々も出土しています。
なお、現在の騎西城は史実に反し天守閣を持つ立派な城として復元されていますが、当時の城は土塁や堀を巡らせた平屋の館でした。ここは郷土史料展示室として前述の出土品などが展示されています。
The date of construction of Kisai Castle and the lord of the castle at the time of construction are unknown, but it was first seen in 1455 that Ashikaga Nariuji attacked the castle which was owned by Uesugi clan lord of Furukawa and was defended by Nagao and Kobanawa clans. Also, in 1563, Uesugi Terutora (Kenshin) took by storm Kisai Castle, which was defended by Oda Sukesaburo. In the 18th year of Tensho (1590), when Tokugawa Ieyasu entered the Kanto region, Matsudaira Yasushige became the lord of Kisai Castle with 20,000 koku. It was Matsudaira Yasushige who founded the Daiei Temple in Kisai and granted the temple territory to the Honei Temple in Hideyasu. Later, Tadatsune and Tadamoto Okubo became the lords of the castle and reorganized Kisai by moving Tamashiki Shrine to its present location. In 1632, Tadayoshi was transferred to Kano Castle in Mino Province, and Kisai Castle was abandoned. Excavations of Kisai Castle since 1930 have revealed that the castle was surrounded by double shoji ditches with a maximum width of 45 meters, indicating that the castle was heavily fortified in preparation for fierce battles. Weapons, armor and daily utensils from the Warring States Period to the early Edo Period have been excavated from the ruins of the castle and samurai residences at Kisai Castle. The unearthed artifacts are diverse, including domestic and foreign ceramics, metal products such as arrowheads, armor fittings, and flint, as well as a large amount of lacquer and wood products. In addition, jet-black helmets, gilded horse stirrups, lacquer bowls with crane designs, clogs, packing slips, spells and talismans were also excavated, all of which vividly bring back the lifestyle of the castle. Although the current Kisai Castle has been restored as a magnificent castle with a castle tower, it went against the historical fact. At that time, the castle was a single-story pavilion with earthen mounds and a moat around it.