This one is easy to get to and takes advantage of its natural surroundings. Be aware of the usual suspects in the desert; things that bite, sting, scratch, etc. Always a good idea to bring some water along.
The cache is on Arizona State Land Trust property and geocachers must purchase a recreation permit available on the Arizona State Land Department's website in order to geocache there. http://asld.secure.force.com/recreationalpermit/
The road is in good shape, though could be a challenge during the monsoons. 2WD vehicles should be OK, though there are some areas of loose sand. High clearance probably not necessary for careful approaches. Use your best judgement.