D.W. Griffith's silent motion-picture version of Ramona, starring Mary Pickford, was filmed at Rancho Camulos and the nearby town of Piru during a two-day shoot on April 1 and 2, 1910. At the time this one-reeler was made, it was billed as the Biograph Company's "most elaborate and artistic movie yet filmed." The chapel, the adobe and patio, and the nearby mountains were all used as backdrops.