Since the DNA is transcribed into mRNA in the nucleus, and
protein synthesis takes place in the cytoplasm, the main body of
the cell, the mRNA has to exit the nucleus to the cytoplasm.The
mRNA is believed to be "tagged" by proteins which serve as export
signals and movedthrough a nuclear pore into the cytoplasm.
The information contained in the nucleotide sequence of the mRNA
is read as three letter words(triplets), called codons. Each word
stands for one amino acid, as well as a couple of nonsense codons.
The synthesis of proteins directed by a mRNA template is called
translation and occurs in a cellular organelle called a Ribosome.
During translation amino acids arelinked together to form a
polypeptide chain which will later be folded into a protein.
During transcription or translation damage to the sequence can
occur, this is known as a mutation and can occur in several ways. A
point mutation, or single base substitution, is a type of mutation
that causes the replacement of a single base nucleotide with
another nucleotide of the genetic material, DNA or RNA. Deletion
mutation is the loss of genetic material. Any number of nucleotides
can be deleted, from a single base to an entire piece of
chromosome. Small deletions are less likely to be fatal; large
deletions are usually fatal -there are always variations based on
which genes are lost.Deletion of a number of base pairs that is not
evenly divisible by three will lead to a frameshift mutation,
causing all of the codons occurring after the deletion to be read
incorrectly during translation, producing a severely altered and
potentially nonfunctional protein.
To find this cache, you need to decrypt the code of life itself.
In order to get all the required letters, I've assigned the
stop/nonsense codons letters(apologies to any genetecists and
protein scientists). As with all translation there is the
possibility of a mutation.These links may help:
http://en.wikipedia.org/wiki/Genetic_code
http://en.wikipedia.org/wiki/Start_codon
http://nobelprize.org/educational_games/medicine/dna/index.html
http://nobelprize.org/educational_games/medicine/gene-code/
Sequence GC1GC0V
augaugauga ugaugaugug ccugccacga gaucucugcc accaauugac
gcacccacuu cauauuuacc uacugaaacg aagaugaagg gcgggaagag
uccacauggu gauuuugaua acguuccgag guagaaaauu ccgaaugcug
aaacgacucc ugggaaagca ccacuuggug agacgaaggc cgagaagaau
cgaacugaau gauaaacuaa acggaguccu uuugacgaac cuacaacauu
aacgaaagcg aauguugaaa ugacucccac gcuccccccu accauuaaaa
uaccaucaac ggga