"Karma Chameleon" is a song by English band Culture Club. The single spent three weeks at number one on the US Billboard Hot 100 in early 1984, becoming the group's biggest hit and only US number-one single among their many Top 10 hits. "Karma Chameleon" was also a huge global hit, hitting number one in 16 countries worldwide, and the Top 10 in several more.
The harmonica part was played by Judd Lander, who had been a member of Merseybeat group The Hideaways in the 1960s. The song was originally to be called "Cameo Chameleon". The band was recorded in interviews in mid-1983 stating this was to be the title of their next single.
Boy George was a very colorful character, and he was a fixture on MTV in the early '80s before American artists began regularly making videos. The video for "Karma Chameleon" was shot on a Mississippi steamboat.